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Pathways Recommended: PI3K/Akt/mTOR
Results for "

AKT inhibitor IV

" in MedChemExpress (MCE) Product Catalog:
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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-14971
    (E)-Akt inhibitor-IV
    1 Publications Verification

    (E)-AKTIV

    		 Akt Cancer
    (E)-Akt inhibitor-IV ((E)-AKTIV) is a PI3K-Akt inhibitor, with potent cytotoxic .
    (E)-<em>Akt</em> <em>inhibitor</em>-<em>IV</em>
  • HY-14971A
    AKT inhibitor IV

    AKTIV

    		 Akt Cancer
    Akt inhibitor-IV (AKTIV) acts as a PI3K-Akt inhibitor at the E isomer (HY-14971), with potent cytotoxicity .
    <em>AKT</em> <em>inhibitor</em> <em>IV</em>
  • HY-158156
    NF-κB-IN-16

    		NF-κB Apoptosis Cancer
    NF-κB-IN-16 (compound 9) is a complex (Pt(IV) complex) of NF-κB inhibitor and Cisplatin (HY-17394), which has high efficacy and low toxicity in anti-tumor activity. active. NF-κB-IN-16 can cause DNA damage, induce mitochondrial dysfunction, produce reactive oxygen species, and induce apoptosis through the mitochondrial pathway and endoplasmic reticulum stress. NF-κB-IN-16 potently inhibits the NF-κB/MAPK signaling pathway and disrupts PI3K/AKT signaling. NF-κB-IN-16 also exhibits excellent in vivo antitumor efficiency and low toxicity in A549 or A549/CDDP xenograft models. .
    NF-κB-IN-16

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